Controlling TRAIL-mediated caspase-3 activation
نویسندگان
چکیده
منابع مشابه
Caspase-mediated p65 cleavage promotes TRAIL-induced apoptosis.
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is cytotoxic to a wide variety of transformed cells, but not to most normal cells, implying potential therapeutic value against advanced cancer. However, signal transduction in TRAIL-mediated apoptosis is not clearly understood compared with other TNF family members. Specifically, it is not yet understood how TRAIL controls n...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2004
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2403497